Key result
Maternal complications in hypertensive pregnancy linked to higher central BP, NT-proBNP, and hs-cTnI.
Why the study?
The study was conducted to compare central blood pressure and cardiac biomarker levels in women with maternal complications of hypertensive disorders of pregnancy.
Are central blood pressure and cardiac biomarkers (NT-proBNP, hs-cTnI) elevated in pregnant women with maternal complications of hypertensive disorders of pregnancy?
Cross-Sectional (n=540)
Are central blood pressure and cardiac biomarkers (NT-proBNP, hs-cTnI) elevated in pregnant women with maternal complications of hypertensive disorders of pregnancy?
Measuring central blood pressure and cardiac biomarkers (NT-proBNP, hs-cTnI) may be useful for screening and monitoring maternal complications in hypertensive pregnancies.
Answers are grounded in this paper and cite their sources.
Should not yet alter HDP management; leaves open whether central BP and biomarkers improve risk prediction.
OBJECTIVE: The main objective of the study was to compare the levels of CBP and these cardiac biomarkers in women with maternal complications of hypertensive disorders of pregnancy (HDP). METHODS: This was a cross-sectional study that enrolled 270 women with HDP and 270 normotensive pregnant controls. Data on basic characteristics and incidence of maternal complications were collected among the two groups. Additionally, information on cardiac biomarkers and CBP was gathered from the women with HDP, to compare the levels of these biomarkers with maternal complications experience by this group. RESULTS: < 0.0001, in cases v. controls, respectively. CONCLUSION: In conclusion, the study found that pregnant hypertensive women with maternal complications had significantly higher median values of CSBP and CDBP, NT-proBNP, and hs-cTnI in compared to those without complications. These findings suggest that measuring these vital signs and cardiac biomarkers in hypertensive pregnancies might be helpful for screening and monitoring maternal complications.
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Mbongozi et al. (2025) conducted a cross-sectional in Hypertensive disorders of pregnancy (n=540). Maternal complications vs. No maternal complications / normotensive controls was evaluated on Levels of central blood pressure, NT-proBNP, and hs-cTnI (p=< 0.0001). Pregnant hypertensive women with maternal complications had significantly higher median values of central blood pressure, NT-proBNP, and hs-cTnI compared to those without complications (P<0.0001).
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