Key result
Contrast-free CnTI echocardiography reveals asymptomatic AHCM indistinct on standard 2D echo.
Why the study?
Unlike classical HCM, apical hypertrophic cardiomyopathy is less explored regarding its diagnosis and long-term outcomes.
Case Report (n=1)
No
Contrast Tuned Imaging (CnTI) echocardiography without intravenous contrast agents can be an effective, non-invasive modality to distinctly delineate apical hypertrophic cardiomyopathy when standard echocardiography is inconclusive.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for non-contrast CnTI in apical HCM; should not yet change practice or guide routine use.
Apical hypertrophic cardiomyopathy (AHCM) is a known entity since its first introduction by Sakamoto and Yamaguchi. However, unlike classical hypertrophic cardiomyopathy (HCM), it is less explored in terms of its associated diagnosis and long-term outcomes. Given the increased availability and utilization of ultra-sophisticated cardiac imaging modalities, AHCM will be increasingly recognized as a distinct, clinically significant variant of classical HCM. It is associated with a wide spectrum of presentation ranging from asymptomatic course with incidental findings on imaging to rarely being associated with ventricular arrhythmias, syncope and sudden cardiac death (SCD). Contrast echocardiography is the most effective and diagnostic study when performed in the right setting with high suspicion on clinical and typical electrocardiogram (ECG) findings. Cardiac magnetic resonance imaging (CMR) has an equal diagnostic yield as a contrast echocardiogram. We are presenting a unique case report of a 57-year old gentleman with asymptomatic AHCM which was distinctly delineated after utilizing contrast tuned imaging (CnTI) echocardiography sans administration of intravenous contrast agents. This is a first case report of AHCM portrayed by this ingenious technology. Keywords: Apical Hypertrophic Cardiomyopathy, LV Contrast Echocardiography, Contrast Tuned Imaging, 4Dimensional XStrain Echocardiography.
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Mehrotra et al. (2023) conducted a case report in Asymptomatic Apical Hypertrophic Cardiomyopathy (n=1). Contrast Tuned Imaging (CnTI) echocardiography without intravenous contrast vs. Standard 2D echocardiography was evaluated on Visualization and diagnosis of apical hypertrophic cardiomyopathy. Contrast tuned imaging (CnTI) echocardiography without intravenous contrast agents successfully delineated asymptomatic apical hypertrophic cardiomyopathy that was indistinct on standard 2D echocardiography.
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