Key result
Clinical and morphological factors are associated with the destabilization and rupture of coronary plaques, leading to acute coronary syndrome in patients with ischaemic heart disease.
Why the study?
Assessing the risk of acute coronary syndrome, identifying predictors of adverse events, and developing prevention and optimal management measures for ischaemic heart disease remain key priorities.
This review discusses clinical and morphological factors associated with coronary plaque destabilization and acute coronary syndrome in patients with ischemic heart disease.
Answers are grounded in this paper and cite their sources.
May inform risk stratification in ischaemic heart disease; hypothesis-generating and requires prospective validation before clinical adoption.
Acute coronary syndrome has for a long time been giving no way of decreasing mortality related to ischaemic heart disease. The primary cause of acute coronary syndrome in the majority of cases is rupture of an unstable atherosclerotic plaque in the coronary artery followed by thrombosis thereof. The main missions of modern cardiology include: assessment of the risk of acute coronary syndrome, identification of predictors of adverse events, and working-out of measures aimed at prevention and optimal management of patients with ischaemic heart disease. This article deals with clinical and morphological factors associated with destabilization of coronary plaques, their rupture, and the development of an acute coronary event.
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Kochergin et al. (2020) conducted a review in Ischaemic heart disease. Clinical and morphological factors are associated with the destabilization and rupture of coronary plaques, leading to acute coronary syndrome in patients with ischaemic heart disease.
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