Key result
Women face a greater intrinsic atrial fibrillation-related risk of stroke than men, necessitating early diagnosis, proactive risk factor identification, and appropriate anticoagulant therapy.
Women face a greater intrinsic AF-related risk of stroke than men, highlighting the need for early diagnosis and appropriate anticoagulant therapy.
Supports sex-specific AF stroke vigilance in practice; leaves open whether guidelines should adopt sex-adjusted thresholds without prospective trials.
Atrial fibrillation (AF) is one of the most commonly occurring arrhythmias and a major modifiable risk factor for stroke, especially in women. While its prevalence is similar in both men and women, women unfortunately face a greater intrinsic AF-related risk of stroke than men do. This is likely one of the reasons that more women than men die from strokes, in addition to experiencing more new and recurrent strokes. Therefore, in women especially, it is imperative to diagnose and treat AF as early as possible. While its unreliable symptom profile and possible intermittent nature can make AF difficult to detect, proactive identification of risk factors and improved detection methods can help. Additionally, the use of risk stratification schemes for anticoagulant therapy, along with the efficacy of nonvitamin K antagonist anticoagulants can enable appropriate therapy to prevent stroke occurrence.
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Prabakaran et al. (2017) conducted a review in Atrial Fibrillation. Women face a greater intrinsic atrial fibrillation-related risk of stroke than men, necessitating early diagnosis, proactive risk factor identification, and appropriate anticoagulant therapy.
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