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January 1, 2014Health and Quality of Life Outcomes35 citationsOpen Access

Is quality of life post cardiac surgery overestimated?

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Why the study?

Are post-cardiac surgery quality of life assessments biased by drop-outs among older, high-risk patients?

Population

1675 patients who underwent cardiac surgery between July 1, 2009 and July 1, 2012, with proven one-year…

Design

Cohort

Follow-up

1 year

Key result

Patients who dropped out of quality of life evaluations one year post cardiac surgery had significantly lower preoperative quality of life, were older, and had higher operative risk compared to those with complete follow-up.

Authors

LNL. Noyez

Discussion

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Overview

Post-cardiac surgery QoL may be overestimated due to selective dropout; leaves open whether bias-adjusted analyses are required in future cohorts.

Study Design

Type

Observational (n=1,675)

Multicenter

No

Structured PICO

Are post-cardiac surgery quality of life assessments biased by drop-outs among older, high-risk patients?

P
Population
1675 patients who underwent cardiac surgery between July 1, 2009 and July 1, 2012, with proven one-year survival and complete preoperative EuroQoL registration (EQ-5D and EQ-VAS).
I
Intervention
Cardiac surgery
O
Outcome
Correlation between age, risk, preoperative QoL and postoperative QoL, and correlation of drop-outs to age, risk and preoperative QoLpatient reported

Quality of life post cardiac surgery is likely overestimated because older, high-risk patients with low preoperative QoL are more likely to drop out of follow-up assessments.

Main Result

Absolute Event Rate: 0.65% vs 0.74%

p-value: p=0.001

Limitations

  • Single institution study
  • Only age, operative risk, and preoperative QoL were included in the analysis, omitting variables like type of operation, gender, frailty, physical activity, and diabetes
  • Missing QoL information is not at random (MNAR), which has consequences for eventual imputation of data
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Cite This Study

L. Noyez (2014) conducted an observational in Post cardiac surgery (n=1,675). Drop-outs (incomplete postoperative QoL) vs. Complete postoperative QoL follow-up was evaluated on Preoperative EQ-5D score (p=0.001). Patients who dropped out of quality of life evaluations one year post cardiac surgery had significantly lower preoperative quality of life, were older, and had higher operative risk compared to those with complete follow-up.

synapsesocial.com/papers/6a1b7d7c6bdb5bd52d1cea5fhttps://doi.org/10.1186/1477-7525-12-62
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic value of preoperative quality of life on mortality after isolated elective myocardial revascularization2012 · 7 citations
  2. 2Evaluation of Quality Of Life after Cardiac Surgery in High-Risk Patients2015 · 6 citations
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  4. 4Health-related quality of life after cardiac surgery – the effects of age, preoperative conditions and postoperative complications2014 · 66 citations
  5. 5Characteristics of longitudinal changes in quality of life and associated factors in patients post cardiac and thoracic aortic surgery: insights from a prospective cohort study2024 · 4 citations