Why the study?
Thrombotic events can complicate assisted reproductive techniques, but data on the weight of risk factors and the potential benefit of thromboprophylaxis are largely lacking.
Does thromboprophylaxis prevent venous thromboembolism in women undergoing assisted reproductive techniques?
Does thromboprophylaxis prevent venous thromboembolism in women undergoing assisted reproductive techniques?
Answers are grounded in this paper and cite their sources.
This review highlights the increasing relevance of thrombotic risk in women undergoing ART and provides clinical practice suggestions for thromboprophylaxis based on available data.
Assisted reproductive techniques (ART) allow infertile couples to conceive. Use of hormones to obtain a controlled ovarian stimulation and an adequate growth of the endometrium preparatory for embryo implantation are not riskless. Among others, thrombotic events can occur during the ovulation induction or pregnancy following ART. As the number of women approaching ART to conceive is steadily increasing, the issue of thrombotic risk in this setting is relevant. Data on the weight of each risk factor and on potential benefit of thromboprophylaxis are largely lacking. In this review, we discuss risk of venous thromboembolism during pregnancy following ART, with a focus on general (i.e.: age, body mass index, thrombophilia, bed rest, transfusions) and ART-specific (i.e., polycystic ovarian syndrome, ovarian hyperstimulation syndrome) risk factors. We also attempt to provide some suggestions to guide clinical practice, based on available data and studies performed outside ART.
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Grandone et al. (2022) studied this question.
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