The Value of Stress Echocardiography in a Young Female Patient With a Negative Stress Electrocardiogram

Stress echocardiography remains a steadfast noninvasive diagnostic test used to determine the presence of obstructive coronary artery disease, along with defining the severity of other disease states (i.e., hypertrophic obstructive cardiomyopathy, regurgitant valve lesions, and right ventricular systolic pressure). Due to its high sensitivity and specificity, stress echocardiographic imaging is advantageous when stress electrocardiography, alone, is not enough to discover true ischemic findings, on a standard Bruce protocol. Even then, false positive and false negative electrocardiogram (EKG) results occur all too frequently. Furthermore, because women may more commonly present with atypical signs of ischemia, additional echocardiographic imaging is beneficial when added to a treadmill stress test to visualize ischemic areas of the myocardium. This case study illustrates the importance of using stress echocardiographic imaging, on a female patient, with false negative EKG findings and atypical chest pain in the presence of coronary artery disease.