What question did this study set out to answer?

To determine the optimal timing for detecting serum lipid abnormalities for preventive care in patients experiencing acute stroke.

March 1, 1987Neurology

Serum lipids after stroke

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To determine the optimal timing for detecting serum lipid abnormalities for preventive care in patients experiencing acute stroke.
Conducted prospective serial analyses of fasting serum lipoproteins on day 1, day 7, and at 3 months post-event.
Evaluated men aged 50 to 69 years presenting with acute cerebral infarction or transient ischemic attacks.
Total cholesterol and LDL cholesterol reached their nadir on day 7, intermediate levels on day 1, and peaked at 3 months, while VLDL and HDL cholesterol changed little.
On day 1, cerebral infarction patients aged 50–59 had significantly lower HDL cholesterol (23 ± 3 vs. 42 ± 5 mg/dl) and a higher total-to-HDL cholesterol ratio (12.7 ± 4.5 vs. 4.7 ± 0.4, p < 0.01) compared to those aged 60–69.
Cerebral infarction patients experienced initial drops in both cholesterol and triglycerides, whereas transient ischemic attack patients aged 60–69 exhibited initial decreases in cholesterol alone.

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Implication

Prospective study demonstrates transient decreases in serum cholesterol following acute cerebral infarction, indicating acute-phase testing may miss treatable dyslipidemia.

Cite This Study

Mendez et al. (1987) studied this question.

synapsesocial.com/papers/6a1bc8b0ea84844e355ef3b5 https://doi.org/10.1212/wnl.37.3.507

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Implication

Prospective study demonstrates transient decreases in serum cholesterol following acute cerebral infarction, indicating acute-phase testing may miss treatable dyslipidemia.

Serum lipids after stroke

Key Points

Discussion

Implication

Cite This Study

Serum lipids after stroke

Key Points

Discussion

Implication

Cite This Study