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December 11, 2002European Heart JournalOpen Access

Electrocardiographic measures of left ventricular hypertrophy show greater heritability than echocardiographic left ventricular mass

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Population

955 members of 229 Caucasian families, ascertained through a hypertensive proband

Comparison

Electrocardiographic measurements of left… vs Echocardiographic measurements of left…

Design

Cross-sectional

Authors

BMBongani M. Mayosi

Discussion

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Overview

May prioritize Sokolow-Lyon voltage for genetic LVH studies; hypothesis-generating and should not yet change practice.

Structured PICO

P
Population
955 members of 229 Caucasian families, ascertained through a hypertensive proband
I
Intervention
Electrocardiographic measurements of left ventricular hypertrophy (Sokolow-Lyon voltage, Cornell voltage, Cornell product, ECG LV mass)
C
Comparator
Echocardiographic measurements of left ventricular mass (M-mode images)
O
Outcome
Heritability estimates of continuous measures of left ventricular hypertrophysurrogate

Electrocardiographic measures of left ventricular hypertrophy, particularly Sokolow-Lyon voltage, demonstrate greater heritability than echocardiographic LV mass, suggesting their utility in genetic studies of cardiac hypertrophy.

Cite This Study

Bongani M. Mayosi (2002) studied this question.

synapsesocial.com/papers/6a1bc9cb26cb5670aa9ce329https://doi.org/10.1053/euhj.2002.3288
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