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Systematic review demonstrates associations between mean platelet volume and diverse conditions, indicating its clinical biomarker potential in coronary and autoimmune disorders.
Platelets have effects on hemostasis, thrombosis, immunity, inflammation, atherosclerosis and angiogenesis. A complete blood count is a routine, easy, and automated technique that provides relevant clinical information. The mean platelet volume (MPV) is a widely investigated blood index associated with platelet size, activity and function. Recent studies have noted that a change in MPV is associated with various disease conditions. The present systematic review was conducted with the aim of providing further understanding regarding a potential correlation between MPV and a wide spectrum of pathologic conditions such as coronary artery disease and autoimmune disease.
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Cho et al. (2025) studied this question.
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