Key result
Case report details the embryological development and physiological role of congenital LAA absence.
Case Report
This paper presents a case report and literature review on the rare congenital absence of the left atrial appendage.
Single-case LAA absence data should not change practice; leaves open long-term outcome questions for prospective study.
The left atrial appendage (LAA) is a small muscular extension arising from the anterolateral wall of the left atrium (LA). LAA contributes to atrial pressure regulation and plays an endocrine and hemodynamic role in cardiovascular physiology (1). During the third to fourth weeks of gestation, the LAA develops from the primordial LA and retains a trabeculated morphology that differs from the smooth-walled LA components formed through incorporation of the pulmonary veins (1).
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Wuzynski et al. (2026) conducted a case report in Congenital absence of the left atrial appendage. Congenital absence of the left atrial appendage is presented in a case report and literature review detailing its embryological development and physiological role.
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