Comprehensive review highlights advanced drug delivery systems for glioblastoma therapy, suggesting improved treatment outcomes through targeting approaches.
Key Points
This review examines recent advancements in drug delivery systems aimed at enhancing therapeutic efficacy in glioblastoma multiforme.
Comprehensive literature review of nanoparticulate and microparticulate systems for drug delivery.
Analysis of mechanisms to overcome blood-brain barrier and improve drug solubility and localization.
Discussion of advanced drug administration routes and future trends in personalized medicine.
Nanoparticulate systems demonstrate improved drug solubility and targeted delivery, effectively bypassing the blood-brain barrier.
Stimuli-responsive systems enable controlled drug release matching tumour characteristics, enhancing therapeutic outcomes.
Challenges related to toxicities and regulatory approvals hinder clinical implementation despite promising advancements.