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July 13, 2020BMJ Innovations

Preliminary design and testing of neck chamber device for baroreflex sensitivity assessment

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Why the study?

Existing neck collar devices generate discomfort due to a tight seal and lack the ability to facilitate unilateral testing and targeted carotid baroreceptor stimulation.

Does a novel strap-free neck chamber device accurately assess baroreflex sensitivity through unilateral carotid baroreceptor stimulation?

Comparison

Novel strap-free neck chamber device providing discrete pressure stimulation from -60 mm Hg to 60 mm Hg

Design

Device design, development, and testing study

Authors

PPPratik V PaliwalIndian Institute of Technology JodhpurPKPrathamesh KambleGovernment Medical CollegeKDK. A. DesaiIndian Institute of Technology Jodhpur

Discussion

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Implication

May enable easier baroreflex assessment; leaves open larger validation before clinical adoption.

Structured PICO

Does a novel strap-free neck chamber device accurately assess baroreflex sensitivity through unilateral carotid baroreceptor stimulation?

P
Population
Individuals undergoing baroreflex sensitivity assessment (specific demographics and sample size not reported)
I
Intervention
Novel strap-free neck chamber device for non-invasive unilateral carotid baroreceptor stimulation (discrete pressure steps from -60 mm Hg to +60 mm Hg)
O
Outcome
Baroreceptor gain determined by changes in heart rate and RR intervalsurrogate

A novel strap-free neck chamber device successfully stimulated individual carotid baroreceptors to assess baroreflex sensitivity, demonstrating feasibility for future clinical applications such as evaluating resistant hypertension.

Cite This Study

Paliwal et al. (2020) studied this question.

synapsesocial.com/papers/6a1bd1ec0a1f7575939cfe2bhttps://doi.org/10.1136/bmjinnov-2019-000390
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Carotid baroreflex control of blood pressure and heart rate in men during dynamic exercise1994 · 148 citations
  2. 2Effects of Autonomic Blockade on the Baroreflex in Man at Rest and During Exercise1972 · 230 citations
  3. 3Role of the Autonomic Nervous System in Modulating Cardiac Arrhythmias2014 · 873 citations
  4. 4The Variable-Pressure Neck-Chamber Method for Studying the Carotid Baroreflex in Man1977 · 134 citations
  5. 5Baroreflex Activation Therapy for the Treatment of Drug-Resistant Hypertension: New Developments2012 · 36 citations