Demonstrates an efficient synthetic strategy for unsymmetrical cyclooctatetraenes, highlighting its modular advantages.
The synthesis of fully substituted, unsymmetrical cyclooctatetraenes (COTs) has long been constrained by multi-step sequences and inefficient cross-couplings of pre-formed COT fragments. We report an auto-tandem palladium catalysis strategy that...
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Guo et al. (2026) studied this question.
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