Following injury, most wounds resolve without any complication. However, if healing is impeded then the wound can become chronic and persist in a non-healing state for months, and even years in some cases. Globally, the majority of chronic wounds have biofilm present that does not resolve unless disrupted. Slough and devitalised tissue need to be removed as they act as a nidus for the biofilm. This article summarises the current methods available for cleaning and debridement and discusses topical antimicrobial treatments used to reduce bioburden.
Valerie Edwards‐Jones (Fri,) studied this question.