Why the study?
Does radiofrequency catheter ablation lead to delayed cure of Wolff-Parkinson-White syndrome in a pediatric patient?
Does radiofrequency catheter ablation lead to delayed cure of Wolff-Parkinson-White syndrome in a pediatric patient?
Ablation-induced lesions may evolve over the first few days, potentially leading to a delayed complete cure even after an initially unsuccessful procedure.
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May indicate delayed lesion effect after failed pediatric WPW ablation; hypothesis-generating and should not change practice.
A 12-year-old female with the Wolff-Parkinson-White syndrome underwent an electrophysiologic study followed by radiofrequency catheter ablation of the left-lateral accessory pathway. After several unsuccessful attempts, the procedure was stopped because of early recurrence of accessory pathway conduction. Twenty-four hours after the procedure, the patient was found without ventricular pre-excitation pattern on the electrocardiogram. During a 12-month follow-up, the Wolff-Parkinson-White pattern was no longer present. A transesophageal electrophysiologic study showed no further tachycardia induction and the patient is still asymptomatic. This report raises the issue that ablation-induced lesions may evolve considerably during the first few days after ablation, leading to either recurrent accessory pathway conduction or long-lasting complete cure.
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Sarubbi et al. (2006) studied this question.
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