Why the study?
To explore the complementary role of CCTA to SPECT MPI in detecting myocardial necrosis.
Does CCTA provide complementary value to SPECT MPI in detecting myocardial necrosis in patients with prior STEMI?
Does CCTA provide complementary value to SPECT MPI in detecting myocardial necrosis in patients with prior STEMI?
CCTA and SPECT MPI play a complementary role in assessing fixed perfusion defects, with CCTA adding specificity to the diagnosis of myocardial necrosis.
May support complementary CCTA-SPECT use post-STEMI; leaves open prospective validation.
PURPOSE: We present this case series exploring the complementary role of coronary computed tomography angiography (CCTA) to SPECT myocardial perfusion imaging (MPI) in the detection of myocardial necrosis. METHODS: A cardiac hybrid imaging database search identified 144 patients with a previous history of ST-segment elevation myocardial infarction treated with coronary revascularization. CCTA and MPI scans were evaluated to determine whether CCTA had an added value to MPI in detecting myocardial necrosis. RESULTS: Five patients with patent stents and/or bypass grafts and both fixed perfusion defects on MPI and sub-endocardial hypo-perfusion on CCTA were identified. The extent and location of the perfusion defects were closely correlated between the CCTA and SPECT MPI images. CONCLUSION: In this series, CCTA and SPECT MPI were found to play a complementary role in the assessment of fixed perfusion defect, with CCTA adding specificity to the diagnosis of myocardial necrosis.
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Abazid et al. (2022) studied this question.
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