Much progress has been made r cently in studies on the adhesive properties of cultured cells. The interest in this field was motivated by two major lines of ob-servation. First, it has been shown that a large number of cellular physiologic processes depend on the for-mation of contacts between the cells and extracellular substances. This phenomenon, which is usually re-ferred to as anchorage dependence, i ludes activities such as control of cell growth and differentiation, the formation of intercellular junctions, and the activation of several metabolic pathways (Stoker and O'Neill 1968; Hay and Meier 1976; Folkman and Moscona
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Benjamin Geiger (1982) studied this question.