Why the study?
Does LAD occlusion produce a larger myocardial infarct relative to occluded bed size compared to LCx occlusion in dogs?
Does LAD occlusion produce a larger myocardial infarct relative to occluded bed size compared to LCx occlusion in dogs?
In a canine model, LAD occlusion results in larger infarcts relative to the occluded bed size compared to LCx occlusion, likely due to lower collateral flow.
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Should not guide human reperfusion decisions; leaves open whether regional collateral differences extend to clinical infarct variability.
Becker et al. (1983) studied this question.
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