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December 1, 1988American Journal of Clinical Pathology

Therapeutic Control of Oral Anticoagulant Treatment in the Netherlands

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Why the study?

What is the most accurate method to assess therapeutic control in anticoagulant clinics, and what level of control is achieved in the Netherlands?

Population

Patients on long-term oral anticoagulant treatment managed by 38 thrombosis centers in the Netherlands

Comparison

Assessment of therapeutic control using the… vs Two other calculation methods for assessing…

Design

Cross-sectional

Authors

ABA M H P van den BesselaarLeiden University Medical CenterFMF.J.M. van der MeerGoethe University FrankfurtCGChristine W. Gerrits-Drabbe

Discussion

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Overview

Supports cross-section method for INR control assessment in clinics; leaves open generalizability beyond this observational Dutch sample.

Structured PICO

What is the most accurate method to assess therapeutic control in anticoagulant clinics, and what level of control is achieved in the Netherlands?

P
Population
Patients on long-term oral anticoagulant treatment managed by 38 thrombosis centers in the Netherlands
I
Intervention
Assessment of therapeutic control using the "cross-section-of-the-files" calculation method
C
Comparator
Two other calculation methods for assessing therapeutic control
O
Outcome
Level of therapeutic control (proportion of time spent within the prothrombin time target range of 2.8-4.8 INR)surrogate

The "cross-section-of-the-files" method is recommended for accurately assessing therapeutic control in anticoagulant clinics, demonstrating high levels of control across Dutch centers.

Cite This Study

Besselaar et al. (1988) studied this question.

synapsesocial.com/papers/6a1bf8a6d54006be995f53fahttps://doi.org/10.1093/ajcp/90.6.685

Topics

Anticoagulation in AF
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Assessment of Therapeutic Control of Anticoagulation2009 · 28 citations
  2. 2Therapeutic control of anticoagulant treatment.1982 · 43 citations
  3. 3Monitoring the effectiveness of anticoagulation control2005 · 3 citations
  4. 4How Effective Is Clinical Control of Anticoagulant Therapy?1965 · 4 citations
  5. 5Interlaboratory Oral Anticoagulant Quality Assessment by the Netherlands Federation of Thrombosis Services1977 · 13 citations