Acute Digitalis Delirium Associated with Intravenous Digoxin Administration

A 77-year-old woman with a reduced ejection fraction was admitted to the hospital for atrial fibrillation with a rapid ventricular rate. Intravenous digoxin was used to slow her ventricular rate. On multiple occasions in the absence of elevated serum digoxin concentrations, she demonstrated multiple episodes of acute delirium associated with the acute intravenous administration of digoxin.