Key result
Patients who recovered from COVID-19 infection had significantly higher left atrial maximum volume (49.2 vs 42.2 ml, P=0.040) and impaired left atrial functions compared to healthy controls.
Why the study?
Left atrial dysfunction is an important risk factor for cardiovascular events, and the effect of recovered COVID-19 infection on LA functions needed evaluation.
Does recovery from COVID-19 affect left atrial functions in adults?
Cross-Sectional (n=120)
Single-blind
No
Does recovery from COVID-19 affect left atrial functions in adults?
Patients who have recovered from COVID-19 exhibit impaired left atrial functions and subclinical left ventricular systolic dysfunction compared to healthy controls, suggesting a need for long-term cardiovascular follow-up.
Answers are grounded in this paper and cite their sources.
COVID-19 recovery was associated with LA impairment; hypothesis-generating for long-term effects, requires prospective validation.
Objective: Left atrial (LA) dysfunction is a crucial risk factor for cardiovascular events, and various pathologies may affect LA function. Coronavirus disease-2019 (COVID-19) is an ongoing global pandemic causing morbidity and mortality. In the present study, we aimed to evaluate LA functions in patients who recovered from COVID-19. Methods: Sixty consecutive patients recovered from COVID-19 and 60 healthy individuals as a control group were included in the study. Blood samples and echocardiography measurements were obtained from each subject. The two groups were compared in terms of demographic and echocardiographic characteristics. Results: In the COVİD-19 group, LA maximum volume (LAV max ) ( P = 0.040), LA pre-A volume (LAVpre-A) ( P = 0.014), and LA active emptying fraction ( P = 0.027) were higher, while LA passive emptying fraction ( P = 0.035) was lower. In addition, left ventricular ejection fraction ( P = 0.006) and isovolumetric relaxation time ( P = 0.008) were decreased in this group. Although LA volume index was higher in the COVID-19 group, it does not reach statistical significance. Conclusion: LA functions may be impaired in patients recovered from COVID-19 infection.
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Ergül et al. (2022) conducted a cross-sectional in COVID-19 (n=120). COVID-19 infection (recovered) vs. Healthy controls was evaluated on Left atrial maximum volume (LA Vmax) in ml (p=0.040). Patients who recovered from COVID-19 infection had significantly higher left atrial maximum volume (49.2 vs 42.2 ml, P=0.040) and impaired left atrial functions compared to healthy controls.
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