Does sex influence in-hospital and long-term outcomes in patients over 75 years of age undergoing percutaneous coronary intervention for coronary heart disease?
In patients over 75 years of age undergoing PCI, sex was not independently associated with in-hospital or long-term mortality, despite differences in baseline presentation.
BACKGROUND: This study aimed to investigate whether there were sex differences in in-hospital and long-term outcomes for elderly patients over 75 years of age undergoing percutaneous coronary intervention for coronary heart disease. METHODS: Consecutive patients aged ≥75 years who underwent percutaneous coronary intervention at a single center in the People's Republic of China from January 2005 to December 2010 were included in this cohort study. Clinical characteristics and in-hospital and long-term outcomes were compared between men and women. RESULTS: A total of 465 patients (34.8% women, mean age 78.5±3.2 years) were recruited. Men had a higher prevalence of ST elevation myocardial infarction but were less likely to have heart failure than women (P<0.05). Similar rates of successful in-hospital procedures and deaths were observed in men and women. After a mean follow-up of 3 years, no significant differences were observed between men and women in mortality (12.5% versus 8.0%, P=0.151), myocardial infarction (1.4% versus 2.7%, P=0.368), target vessel revascularization (6.1% versus 4.7%, P=0.540), or cerebral vascular disease (7.9% versus 6.0%, P=0.472). Cox proportional hazards analysis revealed that sex was not independently associated with either in-hospital mortality or long-term mortality. CONCLUSION: In elderly patients over 75 years of age, sex influences the prognosis after percutaneous coronary intervention for coronary heart disease.
Gao et al. (Wed,) studied this question.