Why the study?
Do isolated Q waves and ventricular extrasystoles on resting ECG predict 16-year mortality in individuals without prior angina or myocardial infarction?
Do isolated Q waves and ventricular extrasystoles on resting ECG predict 16-year mortality in individuals without prior angina or myocardial infarction?
Isolated Q waves and ventricular extrasystoles on resting ECG are independent predictors of long-term cardiovascular and all-cause mortality in asymptomatic individuals.
Answers are grounded in this paper and cite their sources.
Should not yet change practice based on resting ECG alone; extends observational data on ECG predictors but leaves causal implications open.
Isolated abnormalitites in the resting electrocardiograms of 1546 Busselton people with no history of angina or past myocardial infarction were examined in relation to 16 year mortality. Multivariate discriminate analysis in men showed significant independent relationship for Q waves with coronary heart disease and for ventricular extrasystoles with cardiovascular disease. In women multivariate analysis showed significant relations for ventricular extrasystoles with total mortality and coronary heart disease. There were higher trends in mortality for both men and women with frequent ventricular extrasystoles compared with those with infrequent ventricular extrasystoles.
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Cullen et al. (1983) studied this question.
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