The whole is greater than the sum of its parts-this adage holds for the new replication system composed of 1 and 2, which features a very high affinity between complementary components. In this system all reactions proceed via complexes, which minimizes the effects of background reactions. The autocatalysis displayed by the system is shown to arise solely from template effects. R = C6H4C6H4COOC6F5.
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Conn et al. (1994) studied this question.
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