Key result
Hyperglycaemia (random glucose > 11.1 mmol/L) upon admission for acute coronary syndrome was associated with significantly higher one-year mortality compared to those without (27% vs 12%, p=0.002).
Why the study?
Does hyperglycaemia affect one-year mortality in subjects admitted to hospital with an acute coronary syndrome?
Cohort (n=498)
Does hyperglycaemia affect one-year mortality in subjects admitted to hospital with an acute coronary syndrome?
Answers are grounded in this paper and cite their sources.
Hyperglycemia on admission in patients with acute coronary syndromes is associated with a significantly increased risk of one-year mortality.
Diabetes is associated with increased cardiovascular morbidity and mortality. We studied the relationship between hyperglycaemia, troponin I concentrations and one-year mortality in 498 subjects admitted to hospital with an acute coronary syndrome. The proportion of deaths was higher in those with hyperglycaemia (random glucose > 11.1 mmol/L) compared to those without (27% and 12%, respectively, Chi-squared test = 9.84, p=0.002). There was a difference in troponin I concentration on admission between those patients who were alive and dead (median and interquartile range 0.14 [0 to 3.90] and 2.98 [0.23 to 18.53] respectively, p<0.001) and the risk of death was elevated in those with a myocardial infarction compared to those without (relative risk = 1.85, 95% confidence intervals 1.55 to 2.21). Despite adherence to guidelines for the management of acute coronary syndromes, the presence of hyperglycaemia confers a significant long-term mortality disadvantage.
No takes yet. Share an insight, caveat, or question.
Gale et al. (2006) conducted a cohort in Acute coronary syndrome (n=498). Hyperglycaemia (random glucose > 11.1 mmol/L) vs. Without hyperglycaemia was evaluated on One-year mortality (p=0.002). Hyperglycaemia (random glucose > 11.1 mmol/L) upon admission for acute coronary syndrome was associated with significantly higher one-year mortality compared to those without (27% vs 12%, p=0.002).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: