Why the study?
Does infectious mononucleosis increase the risk of developing multiple sclerosis?
Does infectious mononucleosis increase the risk of developing multiple sclerosis?
Answers are grounded in this paper and cite their sources.
Infectious mononucleosis is associated with a significantly increased risk of subsequently developing multiple sclerosis.
By matching a cohort of 494 infectious mononucleosis (IM) cases with a multiple sclerosis (MS) register, 3 MS cases were retrieved. The interval between IM and MS was 12 years. This corresponds to a relative risk of 3.7 for MS to occur subsequent to IM (p = 0.05). This relationship between a manifestation of a relatively late Epstein-Barr virus infection and MS may indicate that a microbiologically shielded environment is important in the pathogenesis of MS.
No takes yet. Share an insight, caveat, or question.
Lindberg et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: