Key result
Postoperative paradoxical septum commonly follows cardiac surgery but carries no negative clinical or functional impact.
Why the study?
Postoperative paradoxical septum occurs frequently after uncomplicated cardiac surgery without negative clinical impact, but its underlying mechanism remains debated.
This review synthesizes 50 years of theories on the postoperative paradoxical septum, proposing that it results from a switch in ventricular anchor points without negative clinical impact.
Reassures clinicians of benign postoperative paradoxical septum; leaves open mechanistic debate after 50 years of theories.
The interventricular septum (IVS) is a core myocardial structure involved in biventricular coupling and performance. Physiologically, during systole, it moves symmetrically toward the center of the left ventricle (LV) and opposite during diastole. Several pathological conditions produce a reversal or paradoxical septal motion, such as after uncomplicated cardiac surgery (CS). The postoperative paradoxical septum (POPS) was observed in a high rate of cases, representing a unicum in the panorama of paradoxical septa as it does not induce significant ventricular morpho-functional alterations nor negative clinical impact. Although it was previously considered a postoperative event, evidence suggests that it might also appear during surgery and gradually resolve over time. The mechanism behind this phenomenon is still debated. In this article, we will provide a comprehensive review of the various theories generated over the past fifty years to explain its pathological basis. Finally, we will attempt to give a heuristic interpretation of the biventricular postoperative motion pattern based on the switch of the ventricular anchor points.
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Virgilio et al. (2024) conducted a review in Postoperative paradoxical septum (POPS) following cardiac surgery. Cardiac surgery was evaluated. Postoperative paradoxical septum is a common phenomenon after cardiac surgery that does not induce significant ventricular morpho-functional alterations or negative clinical impact.
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