Key result
Cardiac MRI detected apical left ventricular aneurysm in 2 (5.1%) and apical thinning in 17 (43.6%) of 39 patients with hypertrophic cardiomyopathy.
Why the study?
Can cardiac MRI effectively detect apical left ventricular aneurysm and thinning in patients with hypertrophic cardiomyopathy?
Observational (n=39)
Can cardiac MRI effectively detect apical left ventricular aneurysm and thinning in patients with hypertrophic cardiomyopathy?
Cardiac MRI effectively identifies apical LV aneurysms and thinning in HCM patients, revealing associations with myocardial hyperenhancement and reduced ejection fraction.
Answers are grounded in this paper and cite their sources.
May support cardiac MRI for apical LV assessment in HCM; leaves open prognostic implications and need for prospective studies.
PURPOSE: To describe magnetic resonance imaging (MRI) findings of apical left ventricular (LV) aneurysm and thinning associated with hypertrophic cardiomyopathy (HCM). METHODS: Thirty-nine patients with HCM underwent cine steady-state, free-precession and delayed contrast-enhanced, inversion-recovery, gradient-echo MRI. An apical LV aneurysm was defined as a thin-walled akinetic aneurysm, and an apical LV thinning was defined as the nonaneurysmal myocardial wall being thinner than 5 mm. The MRI findings were assessed in these patients. RESULTS: Among the 39 patients, 2 showed apical aneurysm and 17 showed apical thinning. Cardiac MRI demonstrated that apical LV aneurysm was associated with myocardial hyperenhancement and a lower ejection fraction and that apical LV thinning was a common finding in HCM with asymmetrical septal hypertrophy. A few patients with apical thinning had some common features to apical aneurysm such as myocardial apical myocardial hyperenhancement. CONCLUSION: Cardiac MRI was useful for the detection of apical LV aneurysm and thinning and the associated findings in HCM.
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Amano et al. (2008) conducted an observational in Hypertrophic cardiomyopathy (n=39). Cardiac Magnetic Resonance Imaging (MRI) was evaluated on Detection of apical left ventricular aneurysm and thinning. Cardiac MRI detected apical left ventricular aneurysm in 2 (5.1%) and apical thinning in 17 (43.6%) of 39 patients with hypertrophic cardiomyopathy.
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