Why the study?
Does template bleeding time correlate with spontaneous bleeding in patients with acute myocardial infarction treated with rt-PA and heparin?
Population
52 consecutive patients with acute myocardial infarction and template bleeding times of less than 9.5 minutes
Design
Cohort
Follow-up
during and after treatment (up to 4 hours measured)
Authors
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90-min bleeding time may flag spontaneous bleeding risk on rt-PA; hypothesis-generating and should not yet change practice.
Does template bleeding time correlate with spontaneous bleeding in patients with acute myocardial infarction treated with rt-PA and heparin?
Prolongation of template bleeding time at 90 minutes during rt-PA therapy for acute myocardial infarction correlates with spontaneous bleeding, particularly in patients taking aspirin.
Gimple et al. (1989) studied this question.
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