Crohn's disease is a chronic inflammatory disorder of unknown aetiology affecting any part of the gastrointestinal tract. Recurrent exacerbations are common but some patients feel mildly unwell even when in remission which makes it difficult to confirm reactivation of the inflammation and to assess disease activity objectively. Yet this assessment is important if appropriate therapy is to be instituted and monitored. This paper reviews the clinical, laboratory and imaging methods used to measure the degree of activity in Crohn's disease.
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Bartholomeusz et al. (1989) studied this question.
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