Key result
In 251 patients undergoing TAVR, aortic angulation (median 46.8° for BE, 43.3° for SE) was not associated with device success or mortality at 30 days and 12 months.
Why the study?
Does increased aortic angulation adversely affect device success or clinical outcomes in patients undergoing balloon-expandable or self-expandable TAVR?
Cohort (n=251)
No
Does increased aortic angulation adversely affect device success or clinical outcomes in patients undergoing balloon-expandable or self-expandable TAVR?
Increased aortic angulation does not adversely impact device success or clinical outcomes in patients undergoing either balloon-expandable or self-expandable TAVR.
Aortic angulation need not influence TAVR valve selection; leaves open confirmation in prospective trials.
OBJECTIVES: The role of aortic angulation in attenuating procedural success in balloon-expandable (BE) and self-expandable (SE) transcatheter aortic valve replacement (TAVR) has been controversial. METHODS: We retrospectively assessed patients undergoing SE and BE TAVR who had an aortic angle measured on multidetector computed tomography at a single tertiary referral center. The primary outcome was device success, measured per the Valve Academic Research Consortium-2 criteria. Clinical outcomes at 30 days (including mortality) were also assessed. RESULTS: A total of 251 patients were identified; 182 patients received a BE valve and 69 patients an SE valve. The median aortic angle was 46.8° (range 24.4-70°) in the BE group and 43.3° (range 20-71°) in the SE group. In multivariate logistic regression analysis, aortic angulation did not affect device success. Mortality at 30 days and 12 months and postprocedural clinical outcomes were similarly not associated with aortic angulation. CONCLUSION: In this cohort of patients undergoing BE and SE TAVR over a wide range of aortic angles, we found no associations between angle and device success or any other clinical metrics. Increased aortic angulation does not adversely affect outcomes in BE or SE TAVR.
No takes yet. Share an insight, caveat, or question.
Elmously et al. (2018) conducted a cohort in Patients undergoing TAVR (n=251). Aortic angulation was evaluated on Device success (Valve Academic Research Consortium-2 criteria). In 251 patients undergoing TAVR, aortic angulation (median 46.8° for BE, 43.3° for SE) was not associated with device success or mortality at 30 days and 12 months.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: