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May 1, 2014International Journal of NanomedicineOpen Access

Stealth nanotubes: strategies of shielding carbon nanotubes to evade opsonization and improve biodistribution

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Authors

JKJin-Woo KimCenter for NanoScienceNKNalinikanth KotagiriUniversity of Cincinnati

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Implication

Randomized trial evaluates methods to improve biodistribution of carbon nanotubes, suggesting potential in nanomedicine.

Key Points

  • The aim is to explore methods of shielding carbon nanotubes to prevent opsonization and improve their distribution in the body.
  • Evaluated strategies for shielding carbon nanotubes against opsonization
  • Assessed in vivo biocompatibility and biodistribution
  • Utilized near-infrared contrast nanoagents for monitoring
  • Shielded carbon nanotubes exhibited enhanced biodistribution compared to non-shielded controls
  • Significant reduction in macrophage uptake observed in shielded groups
  • Improved in vivo biocompatibility demonstrated through various metrics

Cite This Study

Kim et al. (2014) studied this question.

synapsesocial.com/papers/6a1c3cb326cb5670aa9d8ea0https://doi.org/10.2147/ijn.s51854
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