Key result
ANGPTL4 shows therapeutic potential through its fundamental roles in metabolic regulation and tumor growth.
Why the study?
ANGPTL4 is involved in lipid and glucose metabolism, angiogenesis, and tumor growth, prompting an overview of its fundamental role in metabolic regulation and tumor development as a potential therapeutic target.
ANGPTL4 plays a significant role in metabolic regulation and tumor growth, highlighting its potential as a therapeutic target.
Hypothesis-generating for ANGPTL4 modulation; leaves open clinical efficacy and safety pending interventional trials.
Since ANGPTL4 was discovered to be involved in lipid metabolism in 2000 for the first time, Angptl4 has attracted the attention of researchers. With the further research, it was found that angptl4 was also involved in many biological activities (glucose metabolism, angiogenesis, wound healing, tumor growth, etc.) in vivo. In this review, we provide an overview of the fundamental role of ANGPTL4 in metabolic regulation and its impact on tumor growth. These insights may provide a way for exploring ANGPTL4 as a potential therapeutic target for future disease treatments.
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Xu et al. (2024) conducted a review in Metabolic regulation and tumor growth. ANGPTL4 was evaluated. ANGPTL4 plays a fundamental role in metabolic regulation and impacts tumor growth, highlighting its potential as a therapeutic target for future disease treatments.
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