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Aims: The current work was analyzed in antioxidants, cytotoxicity and larvicidal potential were examined for O. latifolia methanolic leaf extract. Methodology: Antioxidant assasy for Hydroxyl radical (H2O2). Cytotoxicity potential was studied against colon (HT-29). Culex quinquefasciatus (IVth instar) larvae was used for larvicidal test. Results: Antioxidant and cytotoxicity exhibits significant activities with IC50 value of 442.94 µg/mL and also the cytotoxicity activity IC50 values of 50.00μg/mL for HT-29. Larval mortality against the larvae of Cx. quinquefasciatus showed best activity with LC50 09.50mg/L and LC90 28.72 mg/L. Conclusion: Thus, this study proved that methanolic leaf extracts of O. latifolia have significant biological activities. Hence, it can be used for pharmacetutical applications.
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R. Gopi Krishnan
S. Murugesh
Journal of Pharmaceutical Research International
Periyar University
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Krishnan et al. (Thu,) studied this question.
synapsesocial.com/papers/6a1c44251567d2fc4d5fd96a — DOI: https://doi.org/10.9734/jpri/2021/v33i46a32866