Key result
Among 13 patients identified with Brugada syndrome phenotypes in an internal medicine setting, 2 had phenotype 1, 4 had phenotype 2, and 7 had phenotype 3.
Observational (n=13)
No
Brugada phenotypes occur in internal medicine; this small series is hypothesis-generating and leaves prevalence and management questions open.
BACKGROUND Brugada syndrome, a disease burdened by elevated risk of sudden unexpected cardiac death, often affects young aged subjects that have structurally healthy heart. The diagnostic itinerary is complex: anamnesis, ECG, pharmacological test and electrophysiological study. Its phenotypes are three. METHOD We have identified 13 cases (10 men and 3 women), 12 estimated at the Cardiological Outpatients' Department and 1 at the First-aid Station. RESULTS 2 cases belonged to phenotype 1, 4 cases to phenotype 2 and 7 cases to phenotype 3. CONCLUSIONS Our work of specialists in internal medicine, toward this syndrome, is: an accurate anamnesis, a correct interpretation of ECG, fast sending of high risk cases to advanced level cardiological competences, a selection of cases to submit to pharmacological test, to address middle risk patients to cardiological competences, offering our cooperation in the follow-up.
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Frabetti et al. (2013) conducted an observational in Brugada syndrome (n=13). Diagnostic screening (ECG, anamnesis, pharmacological test) was evaluated on Brugada syndrome phenotype classification. Among 13 patients identified with Brugada syndrome phenotypes in an internal medicine setting, 2 had phenotype 1, 4 had phenotype 2, and 7 had phenotype 3.
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