Key result
Surgical closure of secundum type atrial septal defect in adult patients resulted in 0% mortality and improved NYHA functional class over a mean follow-up of 36.67 months.
Why the study?
Does surgical closure of secundum type atrial septal defect improve symptoms and reduce mortality in adult patients?
Observational (n=52)
No
Does surgical closure of secundum type atrial septal defect improve symptoms and reduce mortality in adult patients?
Surgical closure of secundum type ASD in adults is safe with zero mortality and significantly improves NYHA functional class at mid-term follow-up.
May support surgical ASD closure decisions in symptomatic adults; leaves open need for randomized confirmation of long-term benefits.
Background: Secundum type atrial septal defect is the most commonly congenital heart disease which has been detected in adults . It is relatively common to observe atrial fibrillation in these patients after the age of fourty. Our study includes the midterm follow-up results of patients who were operated due to secundum type ASD. Methods: 52 adult patients were operated in our clinic between January 2001 and December 2007 due to secundum type atrial septal defect. Mean age was 35.63±12.4 (range 18-60 years) where 37 (71.2%) were female and, 15 (28.8%) were male. The patients were grouped into two with respect to age: Group I included patients aged between 18-40 and Group II included those between 40-60 years of age. 11 patients presented preoperative atrial fibrillation (21.1%). Preoperative mean pulmonary /systemic flow ratio was 2.39 ± 0.59 and mean pulmonary artery pressure was 36.80±9.48. Before the operation 36 patients were in New York Heart Association functional class II (69.2 %), 13 were in class III (25%) and three was in class I (5.8%). Results: Preoperative atrial fibrillation converted to sinus rhythm in 4 of 11 patients in the postoperative period. Postoperative atrial fibrillation continued in five patients in the follow-up period despite the medical treatment. In the follow up period 42 patients were in New York Heart Association functional class I (80.8%) and 10 were in class II (19.2%). Mean follow up period was 36.67±23.12 months. No mortality was observed neither in intraoperative nor in the post operative or follow-up periods. Conclusion: Surgical closure of secundum type atrial septal defect in adult patients and antiarrhytmic therapy in those with atrial fibrillation is a effective method in decreasing morbidity and mortality rates.
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A 2008 study conducted an observational in Secundum type atrial septal defect (n=52). Surgical closure was evaluated on Mortality. Surgical closure of secundum type atrial septal defect in adult patients resulted in 0% mortality and improved NYHA functional class over a mean follow-up of 36.67 months.
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