Key result
Pre-dialysis chronic kidney disease patients had a significantly higher prevalence of carotid atheromatous plaques compared to healthy controls (14.0% vs 2.5%, p<0.05).
Why the study?
CKD patients have high atherosclerotic changes that predict cardiovascular events, prompting evaluation of the prevalence of carotid atherosclerotic plaques in pre-dialysis CKD patients.
Does pre-dialysis CKD increase the prevalence of carotid atheromatous plaques compared to healthy controls?
Case-Control (n=188)
No
Does pre-dialysis CKD increase the prevalence of carotid atheromatous plaques compared to healthy controls?
Pre-dialysis CKD patients have a significantly higher prevalence of carotid atheromatous plaques compared to healthy controls, highlighting the need for early cardiovascular risk assessment in this population.
Answers are grounded in this paper and cite their sources.
Pre-dialysis CKD was associated with higher plaque prevalence; hypothesis-generating for CV risk assessment, requires prospective validation.
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Afolabi et al. (2020) conducted a case-control in Pre-dialysis Chronic Kidney Disease (n=188). Chronic Kidney Disease (Exposure) vs. Healthy controls was evaluated on Prevalence of carotid atheromatous plaques (p=<0.05). Pre-dialysis chronic kidney disease patients had a significantly higher prevalence of carotid atheromatous plaques compared to healthy controls (14.0% vs 2.5%, p<0.05).
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