Key result
Chinese herbal medicines and their isolated compounds, particularly those categorized as heat-clearing and detoxifying, exhibit potential antiviral activity against Enterovirus 71.
Chinese herbal medicines and their isolated compounds represent a potential source for the discovery and development of novel anti-EV71 agents.
Enterovirus 71 (EV71) is one of the causative agents of hand, foot, and mouth disease (HFMD), which sometimes leads to severe neurological disease and death in the Asia-Pacific region. In Chinese medicine, HFMD is caused mainly by an accumulation of damp-heat and toxicity in the body. No effective drugs are currently available for the treatment and prevention of EV71 infection. This review summarizes the potential Chinese herbal extracts and isolated compounds with antiviral activity against EV71 and their clinical applications, especially those categorized as heat-clearing and detoxifying.
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Wang et al. (2016) conducted a review in Enterovirus 71 (EV71) infection. Chinese herbal medicines was evaluated. Chinese herbal medicines and their isolated compounds, particularly those categorized as heat-clearing and detoxifying, exhibit potential antiviral activity against Enterovirus 71.
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