Role of Nose in Sleep-Disordered Breathing

The detailed pathophysiology and mechanisms of sleep-disordered breathing are not completely understood and the role of nose in sleep and obstructive sleep apnea has been still controversial. Considering that nasal obstruction has effects on anatomical factor, neuromuscular factor, and respiratory factor, nose may modulate upper airway collapsibility through anatomical, neuromuscular, and respiratory factors and play an important role of the pathogenesis of obstructive sleep apnea.