Why the study?
Do estimated renal function formulas correlate with 24-hour creatinine clearance in ambulatory elderly subjects?
Population
30 subjects who are ambulatory, functionally independent without severe underlying disease, have normal body…
Comparison
Estimated renal function parameters vs 24-hour creatinine clearance
Design
Cross-sectional
Authors
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Supports Cockcroft-Gault for renal estimation in ambulatory elderly; leaves open prospective outcome validation.
Do estimated renal function formulas correlate with 24-hour creatinine clearance in ambulatory elderly subjects?
Cockcroft-Gault and Lott-Hayton formulas are valid for estimating renal function in healthy ambulatory elderly patients, whereas normal serum creatinine may mask significant renal impairment.
Friedman et al. (1989) studied this question.
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