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Digital preprocessors can ease the increasing data collection demands placed on real-time computers in patient monitoring. This paper describes a preprocessor that detects in real time an electrocardiogram QRS complex and computes the R-R interval. Detection is performed using multiple digital differentiation, which is encouraging as an ultrareliable means for locating the QRS. Inherent in the technique is a dependable control that can automatically compensate for signal-level variations. Clinical data demonstrate that detection is insensitive to low- and high-frequency noise, from baseline drift to muscle artifact and cautery bursts. The device can be connected directly to a patient, whose safety is guaranteed by optoelectronic isolation and interelectrode current limiting. Preprocessor operation has been human-engineered to a simple on/off procedure.
Holsinger et al. (Sat,) studied this question.