Dicoumarol treatment in oxen induces the production of an abnormal, inactive prothrombin variant that differs from normal prothrombin in its calcium-binding and adsorption properties.
No takes yet. Share an insight, caveat, or question.
Suggests dicoumarol induces inactive prothrombin variants in animals; leaves open whether similar mechanisms apply in human anticoagulation.
Stenflo et al. (1972) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: