Key result
Left main coronary artery disease was not associated with a significantly prolonged intensive care unit length of stay compared to patients without left main involvement (65.9 vs 63.4 hours, p=0.6).
Why the study?
The impact of CABG surgery on morbidity and ICU outcomes in patients with LMCA disease needed to be explored.
Does left main coronary artery disease increase intensive care unit length of stay and early morbidity in patients undergoing isolated CABG?
Observational (n=399)
No
Does left main coronary artery disease increase intensive care unit length of stay and early morbidity in patients undergoing isolated CABG?
Absolute Event Rate: 65.9% vs 63.4%
p-value: p=0.6
Patients with left main coronary artery disease undergoing CABG have comparable ICU length of stay and short-term morbidity to those without left main disease.
BACKGROUND: Left main coronary artery (LMCA) supplies more than 80% of the left ventricle, and significant disease of this artery carries a high mortality unless intervened surgically. However, the influence of coronary artery bypass grafting (CABG) surgery on patients with LMCA disease on morbidity intensive care unit (ICU) outcomes needs to be explored. However, the impact of CABG surgery on the morbidity of the ICU population with LMCA disease is worth exploring. AIM: To determine whether LMCA disease is a definitive risk factor of prolonged ICU stay as a primary outcome and early morbidity within the ICU stay as secondary outcome. METHODS: Retrospective descriptive study with purposive sampling analyzing 399 patients who underwent isolated urgent or elective CABG. Patients were divided into 2 groups; those with LMCA disease as group 1 (75 patients) and those without LMCA disease as group 2 (324 patients). We correlated ICU outcome parameters including ICU length of stay, post-operative atrial fibrillation, acute kidney injury, re-exploration, perioperative myocardial infarction, post-operative bleeding in both groups. However, we did not find a statistically significant difference with regards to ICU stay, or other morbidity and mortality outcome measures. CONCLUSION: Post-operative performance of Patients with LMCA disease who underwent CABG were comparable to those without LMCA involvement. Diabetes was more prevalent in patients with LMCA disease. These findings may help in guiding decision making for future practice and stratifying the patients' care.
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Omar et al. (2021) conducted an observational in Left main coronary artery (LMCA) disease undergoing CABG (n=399). Left main coronary artery (LMCA) disease vs. Patients without LMCA disease was evaluated on Length of stay in the intensive care unit (LOS ICU) (p=0.6). Left main coronary artery disease was not associated with a significantly prolonged intensive care unit length of stay compared to patients without left main involvement (65.9 vs 63.4 hours, p=0.6).
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