Why the study?
Does the effective mitral valve area remain constant throughout early rapid left ventricular filling in normal subjects?
Does the effective mitral valve area remain constant throughout early rapid left ventricular filling in normal subjects?
The effective mitral valve area is not constant during early rapid left ventricular filling, which affects the physiological interpretation of the Doppler E wave velocity-time integral.
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Variable EMVA during early filling questions Doppler VTI accuracy for volume; challenges constant-area consensus and requires dynamic models.
Bowman et al. (2004) studied this question.
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