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Clinicians should approach complex CTO interventions cautiously; leaves open the need for dedicated trials on techniques and outcomes.
Interventional cardiology has advanced into domains once believed to be beyond the reach of percutaneous procedures. As technologic advances continue to push the limits of the interventionalist's capabilities, several areas still exert considerable resistance to this forward momentum. These technically difficult frontiers include bifurcated lesions, small-vessel disease, multivessel disease, diffuse disease, and chronic total occlusions.
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Kirvaitis et al. (2006) studied this question.
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