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May 1, 2015PLoS ONEOpen Access

Reversible Changes of Left Atrial Function during Pregnancy Assessed by Two-Dimensional Speckle Tracking Echocardiography

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Why the study?

Does pregnancy alter left atrial function as assessed by 2DSTE compared to healthy nulliparous women?

Population

50 pregnant women and 50 healthy nulliparous women (control group)

Comparison

Pregnancy vs Healthy nulliparous women and 6-month postpartum…

Design

Cohort

Follow-up

6 months postpartum

Authors

GSGuang SongJLJing LiuWRWeidong Ren

Discussion

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Overview

LA changes in pregnancy should not alter management; extends 2DSTE characterization of reversible physiology while leaving prognostic value open.

Structured PICO

Does pregnancy alter left atrial function as assessed by 2DSTE compared to healthy nulliparous women?

P
Population
50 pregnant women and 50 healthy nulliparous women (control group)
I
Intervention
Pregnancy (assessed via two-dimensional speckle tracking echocardiography [2DSTE])
C
Comparator
Healthy nulliparous women (control group) and 6-month postpartum follow-up
O
Outcome
Changes in left atrial (LA) function (reservoir, conduit, and booster pump function) measured by 2DSTEsurrogate

Pregnancy induces reversible changes in left atrial mechanics, specifically increased reservoir and booster pump function and decreased conduit function, which can be reliably assessed using 2DSTE.

Cite This Study

Song et al. (2015) studied this question.

synapsesocial.com/papers/6a1cd0c41fbf86d1e875c8e6https://doi.org/10.1371/journal.pone.0125347
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