The development of reliable continuous glucose monitoring systems requires interdisciplinary collaboration between clinicians, chemists, and engineers.
In the case of the glucose sensor, clinicians and chemists must cooperate in interdisciplinary research to carefully define the analytical problem. Although not specifically discussed in this article, another group that must participate in this effort is engineers. Their expertise is needed to design the monitoring and control unit that contains the alarm and pump systems. The glucose sensor must operate reliably in an in vivo environment, provide the clinical information needed, and be easy to operate and manufacture.
Reach et al. (Sun,) studied this question.
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