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Shows diet restriction improves sleep in mice, highlighting the role of Prdm13 signaling in aging.
This study found that age-associated sleep changes are ameliorated by DR in the presence of Prdm13 signaling in the DMH, suggesting Prdm13+ DMH neurons will be of great interest to explore a potential intervention on age-associated sleep changes.
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Tsuji et al. (2026) studied this question.
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