Cytogenetic studies of bone marrow preparations and/or whole blood cultures were carried out in 18 patients with myeloproliferative disorders. The Ph1 chromosome was detected in six of nine patients with chronic myeloid leukemia. Chromosomal abnormalities included: group C trisomy in a patient with myeloid metaplasia, and a 46 chromosome karyotype but with a missing D group and an extra C group chromosome in a patient with chronic monocytic leukemia.
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Digamber S. Borgaonkar (1972) studied this question.
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